Welcome

Bordeaux Proteome is a scientific and technological platform open to all academic and private scientific communities through the provision of services, materials and expertise in the field of proteomic analysis.

Based on the most innovative technologies and methodologies and the latest generation instruments, Bordeaux Proteome offers services in protein analysis by mass spectrometry and associated separation techniques.

A complete service offer integrating the identification, characterization and quantification / differential analysis of proteins is offered by the platform.

Since 2015, Bordeaux Proteome has been certified ISO 9001 and NF X 50-900. The certified Quality Management System concerns our activities: Research, technological development and expertise in mass spectrometry and proteomics in the fields of Biology, Health and Agronomy.

Our expertise

  • Identification of proteins in complex mixtures.
  • Quantitation and measurement of protein differential expression with / without labeling
  • Characterization of co/post-translational modifications
  • de novo sequencing
  • Protein partners identification (Interactomics, protein complexes).

Our services

One facility

One organization

Several activities

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Differential proteomics

Biomarkers identification

Interactomics

PTMs modifications

Deep Proteome

Clinical cohorts

Multi-omic analysis (proteins, lipids, polysaccharides)

Trace analysis

Taxonomic identification

de novo sequencing

Protein modifications

Spatial distribution on tissues

multi-omics

multi-modal

Exogeneous compound quantification using MALDI MSI

MSI data processing

Glycosylation profiling

Protein complexes

Protein-protein/ligand interactions

Crosslinking

HDX-MS

Affinity-based protein profiling

LiP-MS (limited proteolysis)

Top-Down MS protein characterization

Our services

Sample PreparationProtein and peptide analysisData analysisR&D expertises
For Mass Spectrometry analysisBy high-resolution mass spectrometryBio-informatic treatmentThe M3S team from CBMN
Electrophoretic or chromatographic separation

Protein enrichment or depletion

Peptide sub-species enrichment (phosphoproteomics, glycosylation …)

Various proteolysis solutions: in gel, in solution, multi-enzyme, trace studies …
High resolution MS and nanoLC-MS/MS analyzes (Orbitrap)

Fast or resolving chromatographic gradients

CID, HCD, ETD, EThcD, UVPD fragmentations
Software and hardware dedicated to identification, quantitation and characterization of proteins

Nouveauté 2024: Chimerys, algorithme de recherche en database basé sur l’Intelligence Artificielle (IA)

Omics data integration with the CBiB (bioinformatic cenetr from Bordeaux): statistical validation, Go terms enrichment, visualisation tools and result interpretation, proteome functional annotation
Structural analysis by H/D exchange or cross-linking: conformational studies, interactions, epitope mapping

MSI (Mass Spectrometry Imaging) of lipids, metabolits, peptides/proteins

Intact protein analysis by Top-Down MS

Glycoproteins / glycopeptides analysis

Traces and ultra traces analysis
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