- \n
- Identification of proteins in complex mixtures.<\/li>\n\n\n\n
- Quantitation and measurement of protein differential expression with \/ without labeling<\/li>\n\n\n\n
- Characterization of co\/post-translational modifications<\/li>\n\n\n\n
- de novo sequencing<\/li>\n\n\n\n
- Protein partners identification (Interactomics, protein complexes).<\/li>\n<\/ul>\n\n\n\n
Our services<\/h2>\n\n\n\n
One facility<\/p>\n\n\n\n
One organization<\/p>\n\n\n\n
Several activities<\/p>\n\n\n\n
\n\n![\"Logo](\"https:\/\/i0.wp.com\/proteome.u-bordeaux.fr\/wp-content\/uploads\/2024\/01\/LOGO-DECLI-STEPH-1-copie.png?resize=250%2C250&ssl=1\")
<\/figure>\n<\/div>\n\n\n\n\n![\"Logo](\"https:\/\/i0.wp.com\/proteome.u-bordeaux.fr\/wp-content\/uploads\/2024\/01\/LOGO-DECLI-STEPH-4-copie.png?resize=250%2C250&ssl=1\" "\\"Logo")
<\/figure>\n<\/div>\n\n\n\n\n![\"Logo](\"https:\/\/i0.wp.com\/proteome.u-bordeaux.fr\/wp-content\/uploads\/2024\/01\/LOGO-DECLI-STEPH-6-copie.png?resize=250%2C250&ssl=1\")
<\/figure>\n<\/div>\n\n\n\n\n![\"Logo](\"https:\/\/i0.wp.com\/proteome.u-bordeaux.fr\/wp-content\/uploads\/2024\/01\/LOGO-DECLI-STEPH-10-copie.png?resize=250%2C250&ssl=1\")
<\/figure>\n<\/div>\n<\/div>\n\n\n\n\n\nDifferential proteomics<\/p>\n\n\n\n
Biomarkers identification<\/p>\n\n\n\n
Interactomics<\/p>\n\n\n\n
PTMs modifications<\/p>\n\n\n\n
Deep Proteome<\/p>\n\n\n\n
Clinical cohorts<\/p>\n<\/div>\n\n\n\n
\nMulti-omic analysis\n(proteins, lipids, polysaccharides)<\/p>\n\n\n\n
Trace analysis<\/p>\n\n\n\n
Taxonomic identification<\/p>\n\n\n\n
de novo sequencing<\/p>\n\n\n\n
Protein modifications<\/p>\n<\/div>\n\n\n\n
\nSpatial distribution on tissues<\/p>\n\n\n\n
multi-omics<\/p>\n\n\n\n
multi-modal<\/p>\n\n\n\n
Exogeneous compound quantification using MALDI MSI<\/p>\n\n\n\n
MSI data processing<\/p>\n<\/div>\n\n\n\n
\nGlycosylation profiling<\/p>\n\n\n\n
Protein complexes<\/p>\n\n\n\n
Protein-protein\/ligand interactions<\/p>\n\n\n\n
Crosslinking<\/p>\n\n\n\n
HDX-MS<\/p>\n\n\n\n
Affinity-based protein profiling<\/p>\n\n\n\n
LiP-MS (limited proteolysis)<\/p>\n\n\n\n
Top-Down MS protein characterization<\/p>\n<\/div>\n<\/div>\n\n\n\n
\n\n<\/p>\n<\/div>\n\n\n\n
\nEU-IPERION HS Platform<\/a>
![\"logo](\"https:\/\/i0.wp.com\/proteome.u-bordeaux.fr\/wp-content\/uploads\/2023\/06\/logo-iperion.png?resize=150%2C145&ssl=1\")
<\/a>
ARCHE International Lab Platform<\/a>![\"logo](\"https:\/\/i0.wp.com\/proteome.u-bordeaux.fr\/wp-content\/uploads\/2023\/06\/LOGO-ARCHE-30x9-cm_CMJN-min-2048x768-1.jpg?resize=150%2C56&ssl=1\")
<\/a><\/p>\n<\/div>\n\n\n\n\nGdR Coordination<\/a><\/p>\n\n\n\n
![\"Logo](\"https:\/\/i0.wp.com\/proteome.u-bordeaux.fr\/wp-content\/uploads\/2023\/06\/LOGO-GDR_MSI-1024x732-1.jpg?resize=732%2C210&ssl=1\")
<\/a><\/figure>\n<\/div>\n\n\n\n<\/div>\n<\/div>\n\n\n\nOur services<\/h2>\n\n\n\n
\nSample Preparation<\/strong><\/th> Protein and peptide analysis<\/strong><\/th> Data analysis<\/strong><\/th> R&D expertises<\/strong><\/th><\/tr><\/thead> For Mass Spectrometry analysis<\/em><\/td> By high-resolution mass spectrometry<\/em><\/td> Bio-informatic treatment<\/em><\/td> The M3S team from CBMN<\/em><\/td><\/tr> Electrophoretic or chromatographic separation
Protein enrichment or depletion
Peptide sub-species enrichment (phosphoproteomics, glycosylation \u2026)
Various proteolysis solutions: in gel, in solution, multi-enzyme, trace studies \u2026<\/td>High resolution MS and nanoLC-MS\/MS analyzes (Orbitrap)
Fast or resolving chromatographic gradients
CID, HCD, ETD, EThcD, UVPD fragmentations<\/td>Software and hardware dedicated to identification, quantitation and characterization of proteins
Chimerys, a database search algorithm based on Artificial Intelligence (AI)<\/a><\/mark><\/span>
Omics data integration with the CBiB (bioinformatic cenetr from Bordeaux): statistical validation, Go terms enrichment, visualisation tools and result interpretation, proteome functional annotation<\/td>Structural analysis by isotope exchange or cross-linking: conformational study, interaction, epitope mapping
MSI (Mass Spectrometry Imaging) of lipids, metabolits, peptides\/proteins
Intact protein analysis by Top-Down MS
Glycoproteins \/ glycopeptides analysis
Traces and ultra traces analysis<\/td><\/tr><\/tbody><\/table><\/figure>\n<\/div>","protected":false},"excerpt":{"rendered":"Labellis\u00e9e UAR (Unit\u00e9 d’Appui et de Recherche), en janvier 2026, Bordeaux Proteome est une plateforme scientifique et technologique ouverte \u00e0 l\u2019ensemble des communaut\u00e9s scientifiques, acad\u00e9miques comme priv\u00e9es, par la mise \u00e0 disposition de services, de mat\u00e9riels et d\u2019expertises dans le domaine de l\u2019analyse prot\u00e9omique. S\u2019appuyant sur des technologies et m\u00e9thodologies […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-templates\/template-page-sidebar.php","meta":{"footnotes":""},"class_list":["post-44","page","type-page","status-publish","hentry"],"aioseo_notices":[],"jetpack-related-posts":[],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/proteome.u-bordeaux.fr\/en\/wp-json\/wp\/v2\/pages\/44","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/proteome.u-bordeaux.fr\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/proteome.u-bordeaux.fr\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/proteome.u-bordeaux.fr\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/proteome.u-bordeaux.fr\/en\/wp-json\/wp\/v2\/comments?post=44"}],"version-history":[{"count":147,"href":"https:\/\/proteome.u-bordeaux.fr\/en\/wp-json\/wp\/v2\/pages\/44\/revisions"}],"predecessor-version":[{"id":2240,"href":"https:\/\/proteome.u-bordeaux.fr\/en\/wp-json\/wp\/v2\/pages\/44\/revisions\/2240"}],"wp:attachment":[{"href":"https:\/\/proteome.u-bordeaux.fr\/en\/wp-json\/wp\/v2\/media?parent=44"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}